Peptide record

TPDB87430

RADA16-SVVYGLR Selfassembly modified_plain modified
23 amino acids
Basic Information
TPDB87430
RADA16-SVVYGLR
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 23-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-RADARADARADARADA-SVVYGLR-CONH2
Physicochemical Analysis
C119H196N46O40S2
EQIKMFPTW
A
2975.27
8.29
6
4
13
+1
7.12
-0.373
56.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1615
54.28
5
Residue Composition
number
9
A
5
R
1
N
4
D
2
C
0
E
0
Q
1
G
1
H
0
I
1
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 9 R: 5 N: 1 D: 4 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
23
C119H196N46O40S2
2975.27
8.29
+1
7.12
-0.373
Self-Assembly Information 1 records
Record 1 PMC

Source

10.3389/fbioe.2021.679525
Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine

Self-Assembly

Nanostructure formation
Functionalized RADA16 nanofiber hydrogel
Physiological pH or salt
Selfassembly; Nanostructure=Functionalized RADA16 nanofiber hydrogel; Trigger=Physiological pH or salt
Review reports functionalized RADA16 in zebrafish brain injury model
Brain injury repair angiogenesis
tissue engineering scaffold
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Functionalized RADA16 nanofiber hydrogel Trigger=Physiological pH or salt
Functionalized RADA16 nanofiber hydrogel

Source & Reference

NA
PMC
10.3389/fbioe.2021.679525

Other

N-terminal acetylation C-terminal amidation osteopontin-derived SVVYGLR motif
Brain injury repair angiogenesis
tissue engineering scaffold
Physiological pH or salt
Review reports functionalized RADA16 in zebrafish brain injury model
Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine
Sequence inferred as direct C-terminal extension verify primary article before import.
Additional Detail Fields 6 fields
Physiological pH or salt
N-terminal acetylation C-terminal amidation osteopontin-derived SVVYGLR motif
Sequence inferred as direct C-terminal extension verify primary article before import.
Clinical Use of the Self-Assembling Peptide RADA16: A Review of Current and Future Trends in Biomedicine
Brain injury repair angiogenesis
tissue engineering scaffold