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Peptide record

TPDB87428

RADA16-IKVAV Selfassembly modified_plain modified
21 amino acids
Basic Information
TPDB87428
RADA16-IKVAV
Selfassembly
Self-assembling and biomaterial peptides
ScienceDirect
modified_plain
Yes
A 21-aa modified selfassembly peptide sequence curated from ScienceDirect, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-RADARADARADARADA-IKVAV-CONH2
Physicochemical Analysis
C108H184N42O36S2
EQGLMFPSTWY
A
2711.03
8.30
6
4
13
+1
8.18
-0.216
63.55
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
4.61
3
Residue Composition
number
10
A
4
R
1
N
4
D
2
C
0
E
0
Q
0
G
1
H
1
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 10 R: 4 N: 1 D: 4 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
21
C108H184N42O36S2
2711.03
8.30
+1
8.18
-0.216
Self-Assembly Information 1 records
Record 1 ScienceDirect

Source

10.1016/j.biomaterials.2012.11.043
Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering

Self-Assembly

Nanostructure formation
Functionalized RADA16 nanofiber hydrogel
Physiological aqueous conditions
Selfassembly; Nanostructure=Functionalized RADA16 nanofiber hydrogel; Trigger=Physiological aqueous conditions
CD beta-sheet characterization in article snippet
Brain tissue engineering neural regeneration
tissue engineering scaffold
ScienceDirect
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Functionalized RADA16 nanofiber hydrogel Trigger=Physiological aqueous conditions
Functionalized RADA16 nanofiber hydrogel

Source & Reference

NA
ScienceDirect
10.1016/j.biomaterials.2012.11.043

Other

N-terminal acetylation C-terminal amidation IKVAV motif
Brain tissue engineering neural regeneration
tissue engineering scaffold
Physiological aqueous conditions
CD beta-sheet characterization in article snippet
Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering
Exact sequence reported in source snippet.
Additional Detail Fields 6 fields
Physiological aqueous conditions
N-terminal acetylation C-terminal amidation IKVAV motif
Exact sequence reported in source snippet.
Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering
Brain tissue engineering neural regeneration
tissue engineering scaffold