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Peptide record

TPDB87426

RADA16-GRGDS Selfassembly modified_plain modified
22 amino acids
Basic Information
TPDB87426
RADA16-GRGDS
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 22-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-RADARADARADARADA-GG-GRGDS-CONH2
Physicochemical Analysis
C104H172N46O41S2
EQILKMFPTWYV
A
2786.91
7.01
6
5
9
+0
9.74
-0.821
26.47
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
4.49
4
Residue Composition
number
9
A
5
R
1
N
5
D
2
C
0
E
0
Q
4
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 9 R: 5 N: 1 D: 5 C: 2 E: 0 Q: 0 G: 4 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C104H172N46O41S2
2786.91
7.01
+0
9.74
-0.821
Self-Assembly Information 1 records
Record 1 PMC

Source

Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures

Self-Assembly

Nanostructure formation
Functionalized RADA16 nanofiber scaffold
Physiological pH or salt
Selfassembly; Nanostructure=Functionalized RADA16 nanofiber scaffold; Trigger=Physiological pH or salt
SEM evidence that functional motifs did not prevent nanofiber formation
Neural stem cell culture tissue engineering
tissue engineering scaffold
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Functionalized RADA16 nanofiber scaffold Trigger=Physiological pH or salt
Functionalized RADA16 nanofiber scaffold

Source & Reference

NA
PMC

Other

N-terminal acetylation C-terminal amidation GRGDS motif
Neural stem cell culture tissue engineering
tissue engineering scaffold
Physiological pH or salt
SEM evidence that functional motifs did not prevent nanofiber formation
Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures
RADA16 core extended with fibronectin-derived adhesion motif.
Additional Detail Fields 6 fields
Physiological pH or salt
N-terminal acetylation C-terminal amidation GRGDS motif
RADA16 core extended with fibronectin-derived adhesion motif.
Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures
Neural stem cell culture tissue engineering
tissue engineering scaffold