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Peptide record

TPDB87417

CHL-FFY-YSV Selfassembly modified_plain modified
6 amino acids
Basic Information
TPDB87417
CHL-FFY-YSV
Selfassembly
Self-assembling and biomaterial peptides
ACS
modified_plain
Yes
A 6-aa modified selfassembly peptide sequence curated from ACS, without an available 3D structural model.
Modified, details unspecified
Sequence
chlorambucil-FFY-tyroservatide
Physicochemical Analysis
C131H201N35O36S3
NQGKPW
R
2938.43
7.01
4
3
12
+0
2.21
0.163
68.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
3105
105.67
7
Residue Composition
number
2
A
3
R
0
N
1
D
2
C
2
E
0
Q
0
G
1
H
2
I
2
L
0
K
1
M
2
F
0
P
1
S
2
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 1 C: 2 E: 2 Q: 0 G: 0 H: 1 I: 2 L: 2 K: 0 M: 1 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 2 V: 1
Chemical Descriptors
6
C131H201N35O36S3
2938.43
7.01
+0
2.21
0.163
Self-Assembly Information 1 records
Record 1 ACS

Source

10.1021/acsami.8b18425
Supramolecular Hydrogel Based on Chlorambucil and Peptide Drug for Cancer Combination Therapy

Self-Assembly

Nanostructure formation
Nanofiber supramolecular hydrogel
Peptide-drug conjugate self-assembly
Selfassembly; Nanostructure=Nanofiber supramolecular hydrogel; Trigger=Peptide-drug conjugate self-assembly
Nanofiber hydrogel in vitro/in vivo antitumor assays
Cancer combination therapy
drug carrier active peptide
ACS
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Nanofiber supramolecular hydrogel Trigger=Peptide-drug conjugate self-assembly
Nanofiber supramolecular hydrogel

Source & Reference

NA
ACS
10.1021/acsami.8b18425

Other

Chlorambucil and tyroservatide conjugated to self-assembling peptide
Cancer combination therapy
drug carrier active peptide
Peptide-drug conjugate self-assembly
Nanofiber hydrogel in vitro/in vivo antitumor assays
Supramolecular Hydrogel Based on Chlorambucil and Peptide Drug for Cancer Combination Therapy
Name normalized for seed table verify exact chemical abbreviation before database import.
Additional Detail Fields 6 fields
Peptide-drug conjugate self-assembly
Chlorambucil and tyroservatide conjugated to self-assembling peptide
Name normalized for seed table verify exact chemical abbreviation before database import.
Supramolecular Hydrogel Based on Chlorambucil and Peptide Drug for Cancer Combination Therapy
Cancer combination therapy
drug carrier active peptide