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Peptide record

TPDB87416

CRB-K(HCPT)-FFYG-PMI Selfassembly modified_plain modified
5 amino acids
Basic Information
TPDB87416
CRB-K(HCPT)-FFYG-PMI
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 5-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
Modified, details unspecified
Sequence
CRB-K(HCPT)-FFYG-PMI
Physicochemical Analysis
C78H114N20O17S3
ANDEQLSWV
CFP
1700.07
9.06
3
0
5
+2
-0.41
-0.010
19.50
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1615
95.00
4
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
0
Q
1
G
1
H
1
I
0
L
1
K
1
M
2
F
2
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 0 K: 1 M: 1 F: 2 P: 2 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C78H114N20O17S3
1700.07
9.06
+2
-0.41
-0.010
Self-Assembly Information 1 records
Record 1 PMC

Source

37380607
10.1002/cmdc.202300258
Peptide Assemblies for Cancer Therapy

Self-Assembly

Nanostructure formation
Self-assembled anticancer conjugate assembly
Hydrophobic peptide-drug conjugate assembly
Selfassembly; Nanostructure=Self-assembled anticancer conjugate assembly; Trigger=Hydrophobic peptide-drug conjugate assembly
Review evidence peptide-drug conjugate nanostructure
Cancer therapy
drug carrier active peptide
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Self-assembled anticancer conjugate assembly Trigger=Hydrophobic peptide-drug conjugate assembly
Self-assembled anticancer conjugate assembly

Source & Reference

NA
PMC
10.1002/cmdc.202300258

Other

Chlorambucil hydroxycamptothecin PMI peptide motif
Cancer therapy
drug carrier active peptide
Hydrophobic peptide-drug conjugate assembly
Review evidence peptide-drug conjugate nanostructure
37380607
Peptide Assemblies for Cancer Therapy
Seed row exact primary-source sequence/chemistry needs audit.
Additional Detail Fields 7 fields
Hydrophobic peptide-drug conjugate assembly
Chlorambucil hydroxycamptothecin PMI peptide motif
Seed row exact primary-source sequence/chemistry needs audit.
37380607
Peptide Assemblies for Cancer Therapy
Cancer therapy
drug carrier active peptide