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Peptide record

TPDB87415

FFFK-HCPT Selfassembly modified_plain modified
4 amino acids
Basic Information
TPDB87415
FFFK-HCPT
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 4-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
Modified, details unspecified
Sequence
HCPT-cyclen-FFFK
Physicochemical Analysis
C81H110N18O20S3
ARDQGIMSWV
CF
1752.05
6.91
2
1
5
-0
-0.63
0.125
24.38
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
1615
92.18
6
Residue Composition
number
0
A
0
R
1
N
0
D
3
C
1
E
0
Q
0
G
1
H
0
I
1
L
1
K
0
M
3
F
1
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 3 E: 1 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 1 M: 0 F: 3 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
4
C81H110N18O20S3
1752.05
6.91
-0
-0.63
0.125
Self-Assembly Information 1 records
Record 1 PMC

Source

37380607
10.1002/cmdc.202300258
Peptide Assemblies for Cancer Therapy

Self-Assembly

Nanostructure formation
Supramolecular hydrogel
Self-assembly of peptide-drug conjugate
Selfassembly; Nanostructure=Supramolecular hydrogel; Trigger=Self-assembly of peptide-drug conjugate
Review evidence hydrogel/nuclear delivery study
Cancer therapy
drug carrier active peptide
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Supramolecular hydrogel Trigger=Self-assembly of peptide-drug conjugate
Supramolecular hydrogel

Source & Reference

NA
PMC
10.1002/cmdc.202300258

Other

10-hydroxycamptothecin and cyclen conjugated to FFFK
Cancer therapy
drug carrier active peptide
Self-assembly of peptide-drug conjugate
Review evidence hydrogel/nuclear delivery study
37380607
Peptide Assemblies for Cancer Therapy
Seed from cancer-therapy review primary article should be checked before production import.
Additional Detail Fields 7 fields
Self-assembly of peptide-drug conjugate
10-hydroxycamptothecin and cyclen conjugated to FFFK
Seed from cancer-therapy review primary article should be checked before production import.
37380607
Peptide Assemblies for Cancer Therapy
Cancer therapy
drug carrier active peptide