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Peptide record

TPDB87413

Nap-FF-GPLGLA-RKRK Selfassembly modified_plain modified
12 amino acids
Basic Information
TPDB87413
Nap-FF-GPLGLA-RKRK
Selfassembly
Self-assembling and biomaterial peptides
PubMed
modified_plain
Yes
A 12-aa modified selfassembly peptide sequence curated from PubMed, without an available 3D structural model.
Modified, details unspecified
Sequence
Nap-FF-GPLGLA-RKRK
Physicochemical Analysis
C78H126N24O17
DCEQHIMSTWYV
ARGLKFP
1672.01
12.42
4
0
6
+4
1.22
-0.417
54.44
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
2
K
0
M
2
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 2 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C78H126N24O17
1672.01
12.42
+4
1.22
-0.417
Self-Assembly Information 1 records
Record 1 PubMed

Source

30991000
Enzyme-Triggered Morphological Transition of Peptide Nanostructures for Tumor-Targeted Drug Delivery and Enhanced Cancer Therapy

Self-Assembly

Nanostructure formation
Peptide nanostructures with enzyme-triggered transition
Matrix metalloprotease cleavage
Selfassembly; Nanostructure=Peptide nanostructures with enzyme-triggered transition; Trigger=Matrix metalloprotease cleavage
TEM/DLS-type morphology evidence reported cancer therapy assays
Tumor-targeted drug delivery cancer therapy
drug carrier
PubMed
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Peptide nanostructures with enzyme-triggered transition Trigger=Matrix metalloprotease cleavage
Peptide nanostructures with enzyme-triggered transition

Source & Reference

NA
PubMed

Other

Naphthyl capping group MMP-cleavable GPLGLA motif
Tumor-targeted drug delivery cancer therapy
drug carrier
Matrix metalloprotease cleavage
TEM/DLS-type morphology evidence reported cancer therapy assays
30991000
Enzyme-Triggered Morphological Transition of Peptide Nanostructures for Tumor-Targeted Drug Delivery and Enhanced Cancer Therapy
DOI should be filled after full article audit.
Additional Detail Fields 7 fields
Matrix metalloprotease cleavage
Naphthyl capping group MMP-cleavable GPLGLA motif
DOI should be filled after full article audit.
30991000
Enzyme-Triggered Morphological Transition of Peptide Nanostructures for Tumor-Targeted Drug Delivery and Enhanced Cancer Therapy
Tumor-targeted drug delivery cancer therapy
drug carrier