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Peptide record

TPDB87397

KLD-12-LPP Selfassembly modified_plain modified
30 amino acids
Basic Information
TPDB87397
KLD-12-LPP
Selfassembly
Self-assembling and biomaterial peptides
PMC
modified_plain
Yes
A 30-aa modified selfassembly peptide sequence curated from PMC, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-KLDLKLDLKLDL-GG-DHLSDNYTLDHDRAIH-CONH2
Physicochemical Analysis
C170H271N51O55S2
EQMFPWV
L
3973.45
5.59
8
7
12
-3
10.81
-0.502
90.49
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1615
40.64
7
Residue Composition
number
2
A
1
R
2
N
7
D
2
C
0
E
0
Q
2
G
4
H
1
I
8
L
3
K
0
M
0
F
0
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 7 C: 2 E: 0 Q: 0 G: 2 H: 4 I: 1 L: 8 K: 3 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
30
C170H271N51O55S2
3973.45
5.59
-3
10.81
-0.502
Self-Assembly Information 1 records
Record 1 PMC

Source

32851242
10.7150/thno.43489
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration

Self-Assembly

Nanostructure formation
Injectable hydrogel scaffold
Physiological aqueous conditions
Selfassembly; Nanostructure=Injectable hydrogel scaffold; Trigger=Physiological aqueous conditions
Hydrogel formulation in vivo osteochondral defect repair
Cartilage regeneration
hydrogel scaffold tissue engineering scaffold
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Injectable hydrogel scaffold Trigger=Physiological aqueous conditions
Injectable hydrogel scaffold

Source & Reference

NA
PMC
10.7150/thno.43489

Other

N-terminal acetylation C-terminal amidation LPP motif extension
Cartilage regeneration
hydrogel scaffold tissue engineering scaffold
Physiological aqueous conditions
Hydrogel formulation in vivo osteochondral defect repair
32851242
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration
Functionalized with link protein N-peptide motif to recruit endogenous cells.
Additional Detail Fields 7 fields
Physiological aqueous conditions
N-terminal acetylation C-terminal amidation LPP motif extension
Functionalized with link protein N-peptide motif to recruit endogenous cells.
32851242
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration
Cartilage regeneration
hydrogel scaffold tissue engineering scaffold