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Peptide record

TPDB87396

KLD-12 Selfassembly modified_plain modified
12 amino acids
Basic Information
TPDB87396
KLD-12
Selfassembly
Self-assembling and biomaterial peptides
PMC Peptipedia
modified_plain
Yes
A 12-aa modified selfassembly peptide sequence curated from PMC and Peptipedia, without an available 3D structural model.
C-terminal: Amidation
Sequence
Ac-KLDLKLDLKLDL-CONH2
Physicochemical Analysis
C85H147N23O25S2
REQGIMFPSTWYV
L
1955.36
7.00
4
3
7
+0
4.03
0.033
116.19
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
6.39
3
Residue Composition
number
1
A
0
R
1
N
3
D
2
C
0
E
0
Q
0
G
1
H
0
I
6
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 3 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 6 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C85H147N23O25S2
1955.36
7.00
+0
4.03
0.033
Self-Assembly Information 1 records
Record 1 PMC

Source

32851242
10.7150/thno.43489
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration

Self-Assembly

Nanostructure formation
Hydrogel nanofiber scaffold
Physiological aqueous conditions
Selfassembly; Nanostructure=Hydrogel nanofiber scaffold; Trigger=Physiological aqueous conditions
Self-assembling peptide scaffold in vivo cartilage repair readouts
Cartilage repair tissue engineering
hydrogel scaffold tissue engineering scaffold
PMC
Selfassembly
Evidence Records 1 records
Evidence 1 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel nanofiber scaffold Trigger=Physiological aqueous conditions
Hydrogel nanofiber scaffold

Source & Reference

NA
PMC
10.7150/thno.43489

Other

N-terminal acetylation C-terminal amidation
Cartilage repair tissue engineering
hydrogel scaffold tissue engineering scaffold
Physiological aqueous conditions
Self-assembling peptide scaffold in vivo cartilage repair readouts
32851242
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration
Base KLD-12 scaffold used alone and as parent for functionalized KLD-12-LPP.
Additional Detail Fields 7 fields
Physiological aqueous conditions
N-terminal acetylation C-terminal amidation
Base KLD-12 scaffold used alone and as parent for functionalized KLD-12-LPP.
32851242
Simultaneous Recruitment of Stem Cells and Chondrocytes Induced by a Functionalized Self-Assembling Peptide Hydrogel Improves Endogenous Cartilage Regeneration
Cartilage repair tissue engineering
hydrogel scaffold tissue engineering scaffold