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Peptide record

TPDB77609

SAM 995 Blood-Brain Barrier modified_plain modified
10 amino acids
Basic Information
TPDB77609
SAM 995
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 10-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation
Sequence
YtGFLS-NH2
Physicochemical Analysis
C43H59N11O13
ARDCEQIKMPWV
NGHLFSTY
938.01
7.77
1
0
3
+0
-0.97
-0.330
39.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
158.85
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
1
L
0
K
0
M
1
F
0
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C43H59N11O13
938.01
7.77
+0
-0.97
-0.330
Linear
Similarity
Tyr-(D)Thr-Gly-Phe-Leu-Ser-NH2
O=C(N)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(N)Cc1ccc(O)cc1)C(O)C)Cc2ccccc2)CC(C)C)CO
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.1678 ml/g

Assay & Model

Origin/Source
Volume of donor compartment

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
in situ brain perfusion
Saturable
Additional Detail Fields 1 fields
in situ brain perfusion