Back to search

Peptide record

TPDB77598

Dalargin-SS-SynB3 Blood-Brain Barrier modified_plain modified
33 amino acids
Basic Information
TPDB77598
Dalargin-SS-SynB3
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 33-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation Chemical: Cys-Cys (linker)
Sequence
YaGFLR-C2H4S-SC2H4-RRLSYSRRRF-NH2
Physicochemical Analysis
C129H197N49O32S2
DEQIKMPTWV
R
3010.41
11.73
9
0
7
+6
2.78
-0.797
26.67
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
3105
103.14
9
Residue Composition
number
1
A
6
R
1
N
0
D
2
C
0
E
0
Q
1
G
3
H
0
I
2
L
0
K
0
M
2
F
0
P
4
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 3 I: 0 L: 2 K: 0 M: 0 F: 2 P: 0 S: 4 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
33
C129H197N49O32S2
3010.41
11.73
+6
2.78
-0.797
Cys-Cys (linker)
Linear
Similarity
Tyr-(D)Ala-Gly-Phe-Leu-Arg-NHC2H4S-SC2H4NH-Arg-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe-NH2
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.24 ml/g

Assay & Model

Origin/Source
Volume of donor compartment

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
in situ brain perfusion
Permeability
H3/C14
Additional Detail Fields 1 fields
in situ brain perfusion