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Peptide record

TPDB77580

DPDPE-Arg-Gly Blood-Brain Barrier modified_plain modified
15 amino acids
Basic Information
TPDB77580
DPDPE-Arg-Gly
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 15-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Chemical: Pen2-pen5
Sequence
Y-pen-GF-pen-RG
Physicochemical Analysis
C56H78N16O19
ADCQHILKMSTWV
NEGP
1279.33
4.26
1
2
2
-1
4.54
-1.400
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
116.47
3
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
2
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
15
C56H78N16O19
1279.33
4.26
-1
4.54
-1.400
Pen2-pen5
Linear
Similarity
Tyr-(D)Pen-Gly-Phe-D(Pen)-Arg-Gly
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.000101 cm/s

Assay & Model

BMEC
Origin/Source
Permeability coefficient

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Permeability