TPDB

TPDB ID TPDB77569

Activity

Blood-Brain Barrier

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 43-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

Y-c[cGFC]PQRF-NH2with1stc=cyclic,2ndc=D-Cys

FASTA

>TPDB77569|Blood-Brain Barrier|length=43
Y-c[cGFC]PQRF-NH2with1stc=cyclic,2ndc=D-Cys

Formula C161H225N43O47S9

Absent Amino Acids AEKMV

Common Amino Acids C

Mass 3803.36

PI 5.98

Basic Residues 3

Acidic Residues 2

Hydrophobic Residues 9

Net Charge -1

Boman Index -2.66

Hydrophobicity 0.063

Aliphatic Index 27.21

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 10470

Absorbance 280nm 275.28

Polar Residues 19

number

0

A

1

R

2

N

2

D

9

C

0

E

1

Q

1

G

2

H

2

I

1

L

0

K

0

M

2

F

1

P

2

S

2

T

1

W

3

Y

0

V

Amino Acid Distribution

A: 0 R: 1 N: 2 D: 2 C: 9 E: 0 Q: 1 G: 1 H: 2 I: 2 L: 1 K: 0 M: 0 F: 2 P: 1 S: 2 T: 2 W: 1 Y: 3 V: 0

Length

43

Formula

C161H225N43O47S9

Mass

3803.36

PI

5.98

Net Charge

-1

Boman Index

-2.66

Hydrophobicity

0.063

Evidence 1 Activity

Source & Reference

Database Source NA