TPDB

TPDB ID TPDB77567

Activity

Blood-Brain Barrier

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 84-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

C-terminal: Amidation

Sequence

Y-aminoisobutyricacid-EGTFTSDYSIYLDKQAA-aminoisobutyricacid-EFVNWLLAGGPSSGAPPPSC-NH2

FASTA

>TPDB77567|Blood-Brain Barrier|length=84
Y-aminoisobutyricacid-EGTFTSDYSIYLDKQAA-aminoisobutyricacid-EFVNWLLAGGPSSGAPPPSC-NH2

Formula C336H511N85O104S7

Absent Amino Acids

Common Amino Acids I

Mass 7629.68

PI 4.30

Basic Residues 4

Acidic Residues 6

Hydrophobic Residues 31

Net Charge -3

Boman Index 1.87

Hydrophobicity 0.167

Aliphatic Index 68.69

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 13200

Absorbance 280nm 173.01

Polar Residues 26

number

8

A

2

R

4

N

4

D

5

C

2

E

1

Q

4

G

1

H

9

I

3

L

1

K

2

M

2

F

4

P

7

S

4

T

1

W

5

Y

1

V

Amino Acid Distribution

A: 8 R: 2 N: 4 D: 4 C: 5 E: 2 Q: 1 G: 4 H: 1 I: 9 L: 3 K: 1 M: 2 F: 2 P: 4 S: 7 T: 4 W: 1 Y: 5 V: 1

Length

84

Formula

C336H511N85O104S7

Mass

7629.68

PI

4.30

Net Charge

-3

Boman Index

1.87

Hydrophobicity

0.167

Evidence 1 Activity

Source & Reference

Database Source NA