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Peptide record

TPDB77547

SynB3 Blood-Brain Barrier modified_plain modified
14 amino acids
Basic Information
TPDB77547
SynB3
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 14-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation C-terminal: Chemical modification N-terminal: C-terminal modification
Sequence
RRLSYSRRRF-NH2
Physicochemical Analysis
C70H114N30O17
ADCEQGIKMPTWV
R
1647.87
12.58
6
0
3
+5
3.06
-1.821
27.86
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
90.42
4
Residue Composition
number
0
A
5
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
1
L
0
K
0
M
1
F
0
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C70H114N30O17
1647.87
12.58
+5
3.06
-1.821
Chemical modification
Linear
C-terminal modification
Similarity
Arg-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe-NH2
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.7884 ml/g

Assay & Model

Origin/Source
Volume of donor compartment

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
in situ brain perfusion
Permeability
H3/C14
Additional Detail Fields 1 fields
in situ brain perfusion