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Peptide record

TPDB77546

Orexin B Blood-Brain Barrier modified_plain modified
32 amino acids
Basic Information
TPDB77546
Orexin B
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 32-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation
Sequence
RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
Physicochemical Analysis
C136H227N49O38S1
DCEKFSWYV
GL
3188.66
12.70
5
0
10
+3
5.04
-0.550
82.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
7
Residue Composition
number
3
A
3
R
3
N
0
D
0
C
0
E
3
Q
5
G
2
H
1
I
5
L
0
K
1
M
0
F
3
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 3 D: 0 C: 0 E: 0 Q: 3 G: 5 H: 2 I: 1 L: 5 K: 0 M: 1 F: 0 P: 3 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C136H227N49O38S1
3188.66
12.70
+3
5.04
-0.550
Linear
Similarity
Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
4.4 min

Assay & Model

HPLC
Origin/Source
half life, serum

Source & Reference

NA
B3Pdb

Other

human,pig,mouse,rat,porcine
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
-1.52

Assay & Model

Shake Flask
Origin/Source
Log P

Source & Reference

NA
B3Pdb

Other

human,pig,mouse,rat,porcine
Direct iodination