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Peptide record

TPDB77538

(D)Trp11-Neurotensin Blood-Brain Barrier modified_plain modified
16 amino acids
Basic Information
TPDB77538
(D)Trp11-Neurotensin
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 16-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Pyr-LYENKPRRPwIL
Physicochemical Analysis
C95H145N27O21
ADCQGHMFSTV
RP
2001.36
10.58
4
1
6
+3
2.05
-1.288
73.12
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
8480
423.71
3
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
2
L
1
K
0
M
0
F
3
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
16
C95H145N27O21
2001.36
10.58
+3
2.05
-1.288
Linear
Similarity
Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-(D)Trp-Ile-Leu
O=C(O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC(C)C)Cc2ccc(O)cc2)C(=O)N[C@@H](C(=O)N[C@H](C(=O)N3CCC[C@@H]3C(=O)N[C@H](C(=O)N[C@@H](C(=O)N6[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)O)[C@H](C)CC)[C@@H](C)CC)Cc5c4ccccc4nc5)CCC6)CCCNC(=[N@H])N)CCCNC(=[N@H])N)CCCCN)CC(=O)N
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier

Assay & Model

Origin/Source

Source & Reference

NA
B3Pdb

Other

Chemically synthesized