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Peptide record

TPDB77527

ADAMB Blood-Brain Barrier modified_plain modified
20 amino acids
Basic Information
TPDB77527
ADAMB
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 20-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Nα-amidino-YrF(Me)bA
Physicochemical Analysis
C69H106N18O21S2
CQGHLKPSTWV
ANIM
1587.83
4.07
1
2
8
-1
1.41
-0.030
49.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1490
93.84
3
Residue Composition
number
2
A
1
R
2
N
1
D
0
C
1
E
0
Q
0
G
0
H
2
I
0
L
0
K
2
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 2 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C69H106N18O21S2
1587.83
4.07
-1
1.41
-0.030
Linear
Similarity
Nα-amidino-Tyr-(D)-Arg-Phe-(Me)bAla
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.000029 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional influx rate constant

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Saturable
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.00847 ml/g

Assay & Model

Origin/Source
Initial disrobution volume

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Saturable
Direct iodination
Additional Detail Fields 1 fields
Intravenous