TPDB

TPDB ID TPDB77515

Activity

Blood-Brain Barrier

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 51-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

H-aminoisobutyricacid-EGTFTSDVSSYLEGQAAKEFIAWLVRGRG

FASTA

>TPDB77515|Blood-Brain Barrier|length=51
H-aminoisobutyricacid-EGTFTSDVSSYLEGQAAKEFIAWLVRGRG

Formula C219H340N60O67S3

Absent Amino Acids P

Common Amino Acids AI

Mass 4981.65

PI 5.46

Basic Residues 5

Acidic Residues 5

Hydrophobic Residues 20

Net Charge -1

Boman Index 4.80

Hydrophobicity 0.088

Aliphatic Index 74.71

Half Life

Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 8605

Absorbance 280nm 172.73

Polar Residues 13

number

5

A

3

R

1

N

2

D

2

C

3

E

1

Q

4

G

1

H

5

I

2

L

1

K

1

M

2

F

0

P

4

S

3

T

1

W

2

Y

2

V

Amino Acid Distribution

A: 5 R: 3 N: 1 D: 2 C: 2 E: 3 Q: 1 G: 4 H: 1 I: 5 L: 2 K: 1 M: 1 F: 2 P: 0 S: 4 T: 3 W: 1 Y: 2 V: 2

Length

51

Formula

C219H340N60O67S3

Mass

4981.65

PI

5.46

Net Charge

-1

Boman Index

4.80

Hydrophobicity

0.088

Evidence 1 Activity

Source & Reference

Database Source NA