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Peptide record

TPDB77506

mouse Ghrelin Blood-Brain Barrier modified_plain modified
38 amino acids
Basic Information
TPDB77506
mouse Ghrelin
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 38-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Chemical modification N-terminal: C-terminal modification
Sequence
GSS(octanoyl)FLSPEHQKAQQRKESKKPPAKLQPR
Physicochemical Analysis
C168H274N52O50S1
DIMWV
K
3854.40
10.47
8
2
8
+5
12.28
-1.213
38.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
38.66
12
Residue Composition
number
3
A
2
R
1
N
0
D
1
C
2
E
4
Q
1
G
1
H
0
I
3
L
5
K
0
M
1
F
4
P
4
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 0 C: 1 E: 2 Q: 4 G: 1 H: 1 I: 0 L: 3 K: 5 M: 0 F: 1 P: 4 S: 4 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
38
C168H274N52O50S1
3854.40
10.47
+5
12.28
-1.213
Chemical modification
Linear
C-terminal modification
Similarity
Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.0001852 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional influx rate constant

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Permeability
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.002847 ml/g

Assay & Model

Origin/Source
Initial disrobution volume

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
Permeability
Direct iodination
Additional Detail Fields 1 fields
Intravenous