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Peptide record

TPDB77502

Glycylsarcosine Blood-Brain Barrier modified_plain modified
5 amino acids
Basic Information
TPDB77502
Glycylsarcosine
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 5-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Chemical modification N-terminal: C-terminal modification
Sequence
G-Sar
Physicochemical Analysis
C14H27N7O6
NDCEQHILKMFPTWYV
ARGS
389.41
11.05
1
0
1
+1
0.78
-0.780
20.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C14H27N7O6
389.41
11.05
+1
0.78
-0.780
Chemical modification
Linear
C-terminal modification
Similarity
Gly-Sar
O=C(N(C)CC(=O)O)CN
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.0076 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional flux rate constant

Source & Reference

NA
B3Pdb

Other

human
in situ brain perfusion
Permeability
Additional Detail Fields 1 fields
in situ brain perfusion