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Peptide record

TPDB77499

mouse Obestatin Blood-Brain Barrier modified_plain modified
27 amino acids
Basic Information
TPDB77499
mouse Obestatin
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 27-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
C-terminal: Amidation
Sequence
FNAPFDVGIKLSGAQYQQHGRAL-NH2
Physicochemical Analysis
C124H186N38O35
CEMTW
AQG
2769.07
9.74
4
1
10
+1
3.07
-0.496
65.19
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
53.81
7
Residue Composition
number
3
A
1
R
2
N
1
D
0
C
0
E
3
Q
3
G
2
H
1
I
2
L
1
K
0
M
2
F
1
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 2 D: 1 C: 0 E: 0 Q: 3 G: 3 H: 2 I: 1 L: 2 K: 1 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
27
C124H186N38O35
2769.07
9.74
+1
3.07
-0.496
Linear
Similarity
Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg- Ala-Leu-NH2
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.00186 mL/(g x min)

Assay & Model

Origin/Source
Unidirectional influx rate constant

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
non saturable
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
0.01853 ml/g

Assay & Model

Origin/Source
Initial disrobution volume

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Intravenous
non saturable
Direct iodination
Additional Detail Fields 1 fields
Intravenous