Back to search

Peptide record

TPDB77493

Doxorubicin-SynB1 Blood-Brain Barrier modified_plain modified
37 amino acids
Basic Information
TPDB77493
Doxorubicin-SynB1
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 37-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Doxorubicin-linker-RGGRLSYSRRRFSTSTGR
Physicochemical Analysis
C148H255N57O44S1
AQHMPWV
R
3569.07
12.19
9
2
7
+7
8.03
-0.935
52.70
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
1490
41.75
10
Residue Composition
number
0
A
8
R
2
N
1
D
1
C
1
E
0
Q
3
G
0
H
3
I
2
L
1
K
0
M
1
F
0
P
4
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 2 D: 1 C: 1 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 2 K: 1 M: 0 F: 1 P: 0 S: 4 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
37
C148H255N57O44S1
3569.07
12.19
+7
8.03
-0.935
Linear
Similarity
Doxorubicin-linker-Arg-Gly-Gly-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe-Ser-Thr-Ser-Thr-Gly-Arg
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.0684 mL/(g x min)

Assay & Model

Origin/Source
Unidirectonal influx rate constant

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
In situ perfusion (single time)
Permeability
H3/C14
Additional Detail Fields 1 fields
In situ perfusion (single time)