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Peptide record

TPDB77484

SNX-185 Blood-Brain Barrier modified_plain modified
39 amino acids
Basic Information
TPDB77484
SNX-185
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 39-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Chemical: Cys1-Cys16 Chemical: Cys15-Cys26 Chemical: Cys8-Cys20
Sequence
CLS-Hyp-GSSCS-Hyp-TSYNCCRSCN-Hyp-YSRKCR
Physicochemical Analysis
C161H235N51O49S6
ADEQIMFWV
S
3861.31
8.56
7
0
6
+4
2.85
-0.851
10.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7825
202.65
21
Residue Composition
number
0
A
3
R
2
N
0
D
6
C
0
E
0
Q
1
G
3
H
0
I
1
L
1
K
0
M
0
F
3
P
7
S
1
T
0
W
5
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 0 C: 6 E: 0 Q: 0 G: 1 H: 3 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 7 T: 1 W: 0 Y: 5 V: 0
Chemical Descriptors
39
C161H235N51O49S6
3861.31
8.56
+4
2.85
-0.851
Cys1-Cys16 Cys8-Cys20 Cys15-Cys26
Linear
Similarity
Cys-Leu-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Ser-Arg-Lys-Cys-Arg
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.0000145 cm/s

Assay & Model

BMEC
Origin/Source
Permeability coefficient

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Permeability