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Peptide record

TPDB77483

SNX-194 Blood-Brain Barrier modified_plain modified
29 amino acids
Basic Information
TPDB77483
SNX-194
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 29-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Chemical: Cys1-Cys16 Chemical: Cys15-Cys25 Chemical: Cys8-Cys20
Sequence
CKGKGAKCSRL-Nle-YDCCTGSCRSGKC
Physicochemical Analysis
C112H192N38O38S6
QHIMFPWV
C
2871.35
8.58
6
2
4
+4
6.15
-0.576
30.34
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1865
64.95
12
Residue Composition
number
1
A
2
R
1
N
1
D
6
C
1
E
0
Q
4
G
0
H
0
I
2
L
4
K
0
M
0
F
0
P
3
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 0 L: 2 K: 4 M: 0 F: 0 P: 0 S: 3 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
29
C112H192N38O38S6
2871.35
8.58
+4
6.15
-0.576
Cys1-Cys16 Cys8-Cys20 Cys15-Cys25
Linear
Similarity
Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Nle-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys
Evidence Records 1 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
0.00001083 cm/s

Assay & Model

BMEC
Origin/Source
Permeability coefficient

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Permeability