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Peptide record

TPDB77479

Benzylpenicillin-Syn Blood-Brain Barrier modified_plain modified
35 amino acids
Basic Information
TPDB77479
Benzylpenicillin-Syn
Blood-Brain Barrier
Delivery and barrier-penetrating peptides
Peptipedia
modified_plain
Yes
A 35-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.
Modified, details unspecified
Sequence
Benzylpenicillin-RGGRLSYSRRRFSTSTGR
Physicochemical Analysis
C161H265N53O48S1
ADQHKMWV
R
3743.26
11.03
6
2
10
+4
5.02
-0.586
78.00
Mammalian: Yeast: E.coli:
2980
79.61
12
Residue Composition
number
0
A
6
R
3
N
0
D
1
C
2
E
0
Q
3
G
0
H
3
I
4
L
0
K
0
M
1
F
1
P
4
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 3 D: 0 C: 1 E: 2 Q: 0 G: 3 H: 0 I: 3 L: 4 K: 0 M: 0 F: 1 P: 1 S: 4 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
35
C161H265N53O48S1
3743.26
11.03
+4
5.02
-0.586
Linear
Similarity
Benzylpenicillin-Arg-Gly-Gly-Arg-Leu-Ser-Tyr-Ser-Arg-Arg-Arg-Phe-Ser-Thr-Ser-Thr-Gly-Arg
Evidence Records 2 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
20%

Assay & Model

Capillary depletion
Origin/Source
% capillary

Source & Reference

NA
B3Pdb

Other

mouse
H3/C14
Evidence 2 Activity

Activity

Blood-Brain Barrier
80%

Assay & Model

Capillary depletion
Origin/Source
% parenchyma

Source & Reference

NA
B3Pdb

Other

mouse
Direct iodination