TPDB

TPDB ID TPDB77457

Activity

Blood-Brain Barrier

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 30-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

C-terminal: Amidation

Sequence

Abu-Abu-YaFEVVG-NH<sub>2</sub>

FASTA

>TPDB77457|Blood-Brain Barrier|length=30
Abu-Abu-YaFEVVG-NH<sub>2</sub>

Formula C60H86N16O20

Absent Amino Acids RDCQILKMPTW

Common Amino Acids A

Mass 1351.44

PI 5.13

Basic Residues 1

Acidic Residues 1

Hydrophobic Residues 7

Net Charge -1

Boman Index 1.23

Hydrophobicity 0.103

Aliphatic Index 29.33

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 110.25

Polar Residues 4

number

3

A

0

R

1

N

0

D

0

C

1

E

0

Q

1

G

1

H

0

I

0

L

0

K

0

M

1

F

0

P

2

S

0

T

0

W

1

Y

2

V

Amino Acid Distribution

A: 3 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 2

Length

30

Formula

C60H86N16O20

Mass

1351.44

PI

5.13

Net Charge

-1

Boman Index

1.23

Hydrophobicity

0.103

Evidence 1 Activity

Source & Reference

Database Source NA