TPDB

TPDB ID TPDB77441

Activity

Blood-Brain Barrier

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 76-aa modified blood-brain barrier peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

C-terminal: Amidation

Sequence

(2S)-2-methyl-3-(2,6-dimethyl-4-hydroxyphenyl)propanoicacid-NH-GGFLRRIRPKNH2-NH2

FASTA

>TPDB77441|Blood-Brain Barrier|length=76
(2S)-2-methyl-3-(2,6-dimethyl-4-hydroxyphenyl)propanoicacid-NH-GGFLRRIRPKNH2-NH2

Formula C274H409N83O76S4

Absent Amino Acids QWV

Common Amino Acids H

Mass 6210.01

PI 7.41

Basic Residues 12

Acidic Residues 6

Hydrophobic Residues 18

Net Charge +0

Boman Index 13.87

Hydrophobicity -0.633

Aliphatic Index 43.68

Half Life

Mammalian: Yeast: E.coli:

Extinction Coefficient Cystines 7575

Absorbance 280nm 121.98

Polar Residues 14

number

2

A

5

R

4

N

3

D

2

C

3

E

0

Q

2

G

6

H

4

I

4

L

1

K

2

M

1

F

4

P

1

S

2

T

0

W

5

Y

0

V

Amino Acid Distribution

A: 2 R: 5 N: 4 D: 3 C: 2 E: 3 Q: 0 G: 2 H: 6 I: 4 L: 4 K: 1 M: 2 F: 1 P: 4 S: 1 T: 2 W: 0 Y: 5 V: 0

Length

76

Formula

C274H409N83O76S4

Mass

6210.01

PI

7.41

Net Charge

+0

Boman Index

13.87

Hydrophobicity

-0.633

Evidence 1 Activity

Source & Reference

Database Source NA