TPDB

TPDB ID TPDB77400

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 47-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

YPSKPDFPGEDAPAEDLARYYK-(GFLG-MTX)ALRHYINLITRPRY

FASTA

>TPDB77400|Anticancer|length=47
YPSKPDFPGEDAPAEDLARYYK-(GFLG-MTX)ALRHYINLITRPRY

Formula C226H337N59O62S1

Absent Amino Acids CQWV

Common Amino Acids PY

Mass 4904.58

PI 9.23

Basic Residues 7

Acidic Residues 5

Hydrophobic Residues 18

Net Charge +1

Boman Index 6.29

Hydrophobicity -0.617

Aliphatic Index 58.30

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 7450

Absorbance 280nm 151.90

Polar Residues 9

number

4

A

4

R

1

N

3

D

0

C

2

E

0

Q

3

G

1

H

2

I

4

L

2

K

1

M

2

F

5

P

1

S

2

T

0

W

5

Y

0

V

Amino Acid Distribution

A: 4 R: 4 N: 1 D: 3 C: 0 E: 2 Q: 0 G: 3 H: 1 I: 2 L: 4 K: 2 M: 1 F: 2 P: 5 S: 1 T: 2 W: 0 Y: 5 V: 0

Length

47

Formula

C226H337N59O62S1

Mass

4904.58

PI

9.23

Net Charge

+1

Boman Index

6.29

Hydrophobicity

-0.617

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.