TPDB

TPDB ID TPDB77398

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 57-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

YPSK(GFLG-MTX)PDFPGEDAPAEDLARYYK-(GFLG-MTX)ALRHYINLITRPRY

FASTA

>TPDB77398|Anticancer|length=57
YPSK(GFLG-MTX)PDFPGEDAPAEDLARYYK-(GFLG-MTX)ALRHYINLITRPRY

Formula C254H379N65O69S2

Absent Amino Acids CQWV

Common Amino Acids GLPY

Mass 5511.32

PI 9.23

Basic Residues 7

Acidic Residues 5

Hydrophobic Residues 21

Net Charge +1

Boman Index 4.53

Hydrophobicity -0.386

Aliphatic Index 54.91

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 7450

Absorbance 280nm 135.18

Polar Residues 10

number

4

A

4

R

1

N

3

D

0

C

2

E

0

Q

5

G

1

H

2

I

5

L

2

K

2

M

3

F

5

P

1

S

3

T

0

W

5

Y

0

V

Amino Acid Distribution

A: 4 R: 4 N: 1 D: 3 C: 0 E: 2 Q: 0 G: 5 H: 1 I: 2 L: 5 K: 2 M: 2 F: 3 P: 5 S: 1 T: 3 W: 0 Y: 5 V: 0

Length

57

Formula

C254H379N65O69S2

Mass

5511.32

PI

9.23

Net Charge

+1

Boman Index

4.53

Hydrophobicity

-0.386

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.