TPDB

TPDB ID TPDB77360

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 40-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

RDVFTKGYGFGL-GRK(DANSYLGLYCINE)KRRQRRRPQ

FASTA

>TPDB77360|Anticancer|length=40
RDVFTKGYGFGL-GRK(DANSYLGLYCINE)KRRQRRRPQ

Formula C193H309N65O53S1

Absent Amino Acids HMW

Common Amino Acids R

Mass 4420.04

PI 10.93

Basic Residues 10

Acidic Residues 3

Hydrophobic Residues 11

Net Charge +7

Boman Index 8.48

Hydrophobicity -1.167

Aliphatic Index 48.75

Half Life

Mammalian: 1 hour Yeast: 2 min E.coli: 2 min

Extinction Coefficient Cystines 4470

Absorbance 280nm 101.13

Polar Residues 10

number

1

A

7

R

2

N

2

D

1

C

1

E

2

Q

5

G

0

H

1

I

3

L

3

K

0

M

2

F

1

P

1

S

1

T

0

W

3

Y

1

V

Amino Acid Distribution

A: 1 R: 7 N: 2 D: 2 C: 1 E: 1 Q: 2 G: 5 H: 0 I: 1 L: 3 K: 3 M: 0 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 3 V: 1

Length

40

Formula

C193H309N65O53S1

Mass

4420.04

PI

10.93

Net Charge

+7

Boman Index

8.48

Hydrophobicity

-1.167

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.