TPDB

TPDB ID TPDB77252

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0 dbACP

Sequence_Type

modified_plain

Has_Modification Yes

Description A 59-aa modified anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

FCYWO-CYLEU-PEN-TKKRPKPFQWFWL-CYLEU-KKLMYPTYLKKFQWAV-AIB-HL

FASTA

>TPDB77252|Anticancer|length=59
FCYWO-CYLEU-PEN-TKKRPKPFQWFWL-CYLEU-KKLMYPTYLKKFQWAV-AIB-HL

Formula C303H431N67O65S4

Absent Amino Acids DGS

Common Amino Acids K

Mass 6180.41

PI 9.52

Basic Residues 9

Acidic Residues 3

Hydrophobic Residues 24

Net Charge +5

Boman Index -3.09

Hydrophobicity -0.308

Aliphatic Index 54.58

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 29575

Absorbance 280nm 478.53

Polar Residues 13

number

2

A

1

R

1

N

0

D

3

C

3

E

2

Q

0

G

1

H

1

I

6

L

7

K

1

M

4

F

4

P

0

S

2

T

4

W

5

Y

1

V

Amino Acid Distribution

A: 2 R: 1 N: 1 D: 0 C: 3 E: 3 Q: 2 G: 0 H: 1 I: 1 L: 6 K: 7 M: 1 F: 4 P: 4 S: 0 T: 2 W: 4 Y: 5 V: 1

Length

59

Formula

C303H431N67O65S4

Mass

6180.41

PI

9.52

Net Charge

+5

Boman Index

-3.09

Hydrophobicity

-0.308

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0 dbACP

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.