TPDB

TPDB ID TPDB77210

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 27-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

AAA-RRP-HYP-G-THI-S-F-ACC-R

FASTA

>TPDB77210|Anticancer|length=27
AAA-RRP-HYP-G-THI-S-F-ACC-R

Formula C91H140N32O23S2

Absent Amino Acids NDEQLKMWV

Common Amino Acids A

Mass 2114.43

PI 9.92

Basic Residues 5

Acidic Residues 0

Hydrophobic Residues 7

Net Charge +3

Boman Index 1.99

Hydrophobicity -0.252

Aliphatic Index 29.26

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 76.38

Polar Residues 5

number

4

A

3

R

0

N

0

D

2

C

0

E

0

Q

1

G

2

H

1

I

0

L

0

K

0

M

1

F

2

P

1

S

1

T

0

W

1

Y

0

V

Amino Acid Distribution

A: 4 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 2 I: 1 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 0

Length

27

Formula

C91H140N32O23S2

Mass

2114.43

PI

9.92

Net Charge

+3

Boman Index

1.99

Hydrophobicity

-0.252

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.