TPDB

TPDB ID TPDB77207

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

modified_plain

Has_Modification Yes

Description A 35-aa modified anticancer peptide sequence curated from CancerPPD 2.0, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

AAA-RRP-HYP-G-THI-S-(D)PIP-(L)PIP-R

FASTA

>TPDB77207|Anticancer|length=35
AAA-RRP-HYP-G-THI-S-(D)PIP-(L)PIP-R

Formula C115H182N36O29

Absent Amino Acids NCEQKMFWV

Common Amino Acids P

Mass 2532.93

PI 11.06

Basic Residues 5

Acidic Residues 1

Hydrophobic Residues 8

Net Charge +2

Boman Index 5.62

Hydrophobicity -0.386

Aliphatic Index 53.14

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 58.83

Polar Residues 3

number

3

A

3

R

0

N

1

D

0

C

0

E

0

Q

1

G

2

H

3

I

1

L

0

K

0

M

0

F

6

P

1

S

1

T

0

W

1

Y

0

V

Amino Acid Distribution

A: 3 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 3 L: 1 K: 0 M: 0 F: 0 P: 6 S: 1 T: 1 W: 0 Y: 1 V: 0

Length

35

Formula

C115H182N36O29

Mass

2532.93

PI

11.06

Net Charge

+2

Boman Index

5.62

Hydrophobicity

-0.386

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.