TPDB

TPDB ID TPDB73323

Activity

Quorum sensing

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 129-aa modified quorum sensing peptide sequence curated from Peptipedia, without an available 3D structural model.

Modification

Modified, details unspecified

Sequence

A(Abu)F(Abu)LPGGGGVA(Abu)L(Abu)(Dha)EAI,cyclisationbetween(Ala1-S-Abu2),(Abu4-S-Ala12),(Abu13-S-Ala18)and(Ile19-NH-CH=CH-S-Abu15)

FASTA

>TPDB73323|Quorum sensing|length=129
A(Abu)F(Abu)LPGGGGVA(Abu)L(Abu)(Dha)EAI,cyclisationbetween(Ala1-S-Abu2),(Abu4-S-Ala12),(Abu13-S-Ala18)and(Ile19-NH-CH=CH-S-Abu15)

Formula C281H435N79O93S4

Absent Amino Acids RQKM

Common Amino Acids A

Mass 6536.26

PI 4.26

Basic Residues 4

Acidic Residues 7

Hydrophobic Residues 35

Net Charge -7

Boman Index 6.13

Hydrophobicity 0.275

Aliphatic Index 51.01

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 7240

Absorbance 280nm 110.77

Polar Residues 16

number

20

A

0

R

4

N

2

D

4

C

5

E

0

Q

4

G

4

H

4

I

7

L

0

K

0

M

1

F

1

P

5

S

2

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 20 R: 0 N: 4 D: 2 C: 4 E: 5 Q: 0 G: 4 H: 4 I: 4 L: 7 K: 0 M: 0 F: 1 P: 1 S: 5 T: 2 W: 1 Y: 1 V: 1

Length

129

Formula

C281H435N79O93S4

Mass

6536.26

PI

4.26

Net Charge

-7

Boman Index

6.13

Hydrophobicity

0.275

Evidence 1 Activity

Source & Reference

Database Source NA