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Peptide record

TPDB72747

Neurotoxin standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB72747
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 40-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
SDGRDAAVIYTESDVIARGDCKPCMHPDCRFNPGRCRPRE
Physicochemical Analysis
C184H294N62O60S5
QLW
R
4495.04
6.86
8
7
10
-0
15.40
-0.895
41.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1740
38.71
9
Residue Composition
number
3
A
6
R
1
N
5
D
4
C
2
E
0
Q
3
G
1
H
2
I
0
L
1
K
1
M
1
F
4
P
2
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 6 N: 1 D: 5 C: 4 E: 2 Q: 0 G: 3 H: 1 I: 2 L: 0 K: 1 M: 1 F: 1 P: 4 S: 2 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
40
C184H294N62O60S5
4495.04
6.86
-0
15.40
-0.895
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target. Possibly targets ion channels. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus betulinus (Beech cone)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target. Possibly targets ion channels..
Conotoxin Bt14.16
cone snail
Conotoxin A superfamily
Evidence at protein level
3D-structure Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
Additional Detail Fields 7 fields
3D-structure Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin A superfamily
Conotoxin Bt14.16
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305}.
cone snail