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Peptide record

TPDB72725

Neurotoxin standard
131 amino acids
Basic Information
3D PDB MODEL
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TPDB72725
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 131-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLLLTLLLGSALMCITLADECGLGTHRPVKEVIDNVRTMYYCDCRAGDAERSITVSRCDDNNQKQDDVILTYCGLEQTTGCNTNPYTAAKHDSSGDKPQFYCSCLNYKYEQSHSDYRHWTIRCYMGNICD
Physicochemical Analysis
C632H989N179O206S15
DL
14871.78
5.35
17
17
44
-4
25.91
-0.470
69.24
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
19535
131.36
51
Residue Composition
number
6
A
7
R
7
N
12
D
11
C
5
E
5
Q
8
G
4
H
6
I
12
L
6
K
4
M
1
F
3
P
8
S
11
T
1
W
9
Y
5
V
Amino Acid Distribution
A: 6 R: 7 N: 7 D: 12 C: 11 E: 5 Q: 5 G: 8 H: 4 I: 6 L: 12 K: 6 M: 4 F: 1 P: 3 S: 8 T: 11 W: 1 Y: 9 V: 5
Chemical Descriptors
131
C632H989N179O206S15
14871.78
5.35
-4
25.91
-0.470
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target. Possibly targets ion channels. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Californiconus californicus (California cone) (Conus californicus)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target. Possibly targets ion channels..
Conotoxin Cal8.1 (Conotoxin CalMKLL-1)
cone snail
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
Additional Detail Fields 6 fields
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Conotoxin Cal8.1 (Conotoxin CalMKLL-1)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
cone snail