TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB72714

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 115-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSSIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG

FASTA

>TPDB72714|Neurotoxin|length=115
MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSSIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG

Formula C586H897N151O178S11

Absent Amino Acids

Common Amino Acids K

Mass 13258.13

PI 5.23

Basic Residues 20

Acidic Residues 21

Hydrophobic Residues 41

Net Charge -4

Boman Index 33.23

Hydrophobicity -0.494

Aliphatic Index 59.39

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 11960

Absorbance 280nm 90.21

Polar Residues 28

number

7

A

4

R

1

N

10

D

8

C

11

E

3

Q

6

G

3

H

2

I

10

L

13

K

3

M

9

F

3

P

8

S

4

T

1

W

4

Y

5

V

Amino Acid Distribution

A: 7 R: 4 N: 1 D: 10 C: 8 E: 11 Q: 3 G: 6 H: 3 I: 2 L: 10 K: 13 M: 3 F: 9 P: 3 S: 8 T: 4 W: 1 Y: 4 V: 5

Length

115

Formula

C586H897N151O178S11

Mass

13258.13

PI

5.23

Net Charge

-4

Boman Index

33.23

Hydrophobicity

-0.494

Evidence 1 Activity

Source & Reference

Database Source NA