TPDB

3D PDB MODEL

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TPDB ID TPDB72680

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 306-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MAAIIVHGGAGTIRKEERIPKVIEGVREAVLAGWRELKRGSALDAVEEAVKALEDNPIFNAGTGSVLTLDGKVEMDAAIMRGKTLDAGAVAGIWGVKNPISVARKVMEKTDHVLLIGEGAVKFARLLGFEEYDPITEERLKQWEELRKKLIEKGETKHWKKLNELIKEYPEVLRSTVGAVAFDGEEVVAGTSTGGVFLKMFGRVGDTPIIGGGTYANEVAGASCTGLGEVAIKLALAKSAADFVRLGMDAQTASEAAISLATKYFGPDTMGIIMVDAKGNVGFAKNTKHMSYAFMKDGMDEPEAGV

FASTA

>TPDB72680|Neurotoxin|length=306
MAAIIVHGGAGTIRKEERIPKVIEGVREAVLAGWRELKRGSALDAVEEAVKALEDNPIFNAGTGSVLTLDGKVEMDAAIMRGKTLDAGAVAGIWGVKNPISVARKVMEKTDHVLLIGEGAVKFARLLGFEEYDPITEERLKQWEELRKKLIEKGETKHWKKLNELIKEYPEVLRSTVGAVAFDGEEVVAGTSTGGVFLKMFGRVGDTPIIGGGTYANEVAGASCTGLGEVAIKLALAKSAADFVRLGMDAQTASEAAISLATKYFGPDTMGIIMVDAKGNVGFAKNTKHMSYAFMKDGMDEPEAGV

Formula C1451H2344N392O436S12

Absent Amino Acids

Common Amino Acids A

Mass 32641.66

PI 5.49

Basic Residues 43

Acidic Residues 44

Hydrophobic Residues 137

Net Charge -5

Boman Index 79.38

Hydrophobicity -0.032

Aliphatic Index 91.54

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 29450

Absorbance 280nm 90.22

Polar Residues 42

number

38

A

13

R

7

N

15

D

1

C

29

E

2

Q

37

G

4

H

19

I

23

L

26

K

11

M

10

F

8

P

10

S

17

T

4

W

5

Y

27

V

Amino Acid Distribution

A: 38 R: 13 N: 7 D: 15 C: 1 E: 29 Q: 2 G: 37 H: 4 I: 19 L: 23 K: 26 M: 11 F: 10 P: 8 S: 10 T: 17 W: 4 Y: 5 V: 27

Length

306

Formula

C1451H2344N392O436S12

Mass

32641.66

PI

5.49

Net Charge

-5

Boman Index

79.38

Hydrophobicity

-0.032

Evidence 1 Activity

Source & Reference

Database Source NA