TPDB

3D PDB MODEL

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TPDB ID TPDB72581

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 75-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKSSMAILLVMALIIFTLDKNYSTAKDLPSCEKGIHRKVTCKQCNKRSDNDDDYTKCCNSFDAFLMCGFLLSKES

FASTA

>TPDB72581|Neurotoxin|length=75
MKSSMAILLVMALIIFTLDKNYSTAKDLPSCEKGIHRKVTCKQCNKRSDNDDDYTKCCNSFDAFLMCGFLLSKES

Formula C366H593N97O113S10

Absent Amino Acids W

Common Amino Acids K

Mass 8480.92

PI 8.01

Basic Residues 12

Acidic Residues 9

Hydrophobic Residues 28

Net Charge +2

Boman Index 13.45

Hydrophobicity -0.169

Aliphatic Index 75.47

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 3355

Absorbance 280nm 39.56

Polar Residues 25

number

4

A

2

R

4

N

7

D

6

C

2

E

1

Q

2

G

1

H

4

I

8

L

9

K

4

M

4

F

1

P

8

S

4

T

0

W

2

Y

2

V

Amino Acid Distribution

A: 4 R: 2 N: 4 D: 7 C: 6 E: 2 Q: 1 G: 2 H: 1 I: 4 L: 8 K: 9 M: 4 F: 4 P: 1 S: 8 T: 4 W: 0 Y: 2 V: 2

Length

75

Formula

C366H593N97O113S10

Mass

8480.92

PI

8.01

Net Charge

+2

Boman Index

13.45

Hydrophobicity

-0.169

Evidence 1 Activity

Source & Reference

Database Source NA