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Peptide record

TPDB72548

Neurotoxin standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB72548
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 38-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
GTTCYCGSTLGIYWFAVSSCPSGRGYTGHCGYFLGLCC
Physicochemical Analysis
C176H252N44O51S6
NDEQKM
G
3992.56
7.63
2
0
13
+1
-8.02
0.471
51.32
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11835
296.43
18
Residue Composition
number
1
A
1
R
0
N
0
D
6
C
0
E
0
Q
8
G
1
H
1
I
3
L
0
K
0
M
2
F
1
P
4
S
4
T
1
W
4
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 6 E: 0 Q: 0 G: 8 H: 1 I: 1 L: 3 K: 0 M: 0 F: 2 P: 1 S: 4 T: 4 W: 1 Y: 4 V: 1
Chemical Descriptors
38
C176H252N44O51S6
3992.56
7.63
+1
-8.02
0.471
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Possible modulator of crustacean voltage-gated sodium channels (Nav). {ECO:0000269|PubMed:20483220}.

Target

voltage-gated sodium channel (Nav)

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Bunodosoma cangicum (Sea anemone)
Neurotoxin Ion channel impairing toxin Voltage-gated sodium channel impairing toxin
Possible modulator of crustacean voltage-gated sodium channels (Nav)..
Toxin Bcg III 31.16 (Toxin Bcg 31.16)
sea anemone
Sea anemone type 3 (BDS) potassium channel toxin family
Evidence at protein level
Direct protein sequencing Disulfide bond Ion channel impairing toxin Nematocyst Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin
Additional Detail Fields 6 fields
Direct protein sequencing Disulfide bond Ion channel impairing toxin Nematocyst Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin
Neurotoxin Ion channel impairing toxin Voltage-gated sodium channel impairing toxin
Evidence at protein level
Sea anemone type 3 (BDS) potassium channel toxin family
Toxin Bcg III 31.16 (Toxin Bcg 31.16)
sea anemone