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Peptide record

TPDB72539

Neurotoxin standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB72539
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 45-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
CMTICTMEYWPVCGSDGKTYPNKCHLTSTACTSQKDITVLHEGKC
Physicochemical Analysis
C210H332N56O68S8
RF
T
4985.76
6.91
6
4
12
-0
8.28
-0.280
49.78
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
8855
177.61
20
Residue Composition
number
1
A
0
R
1
N
2
D
6
C
2
E
1
Q
3
G
2
H
2
I
2
L
4
K
2
M
0
F
2
P
3
S
7
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 2 C: 6 E: 2 Q: 1 G: 3 H: 2 I: 2 L: 2 K: 4 M: 2 F: 0 P: 2 S: 3 T: 7 W: 1 Y: 2 V: 2
Chemical Descriptors
45
C210H332N56O68S8
4985.76
6.91
-0
8.28
-0.280
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Acts as a neurotoxin by inhibiting an ion channel (By similarity). May also act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature. {ECO:0000250}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Lophiotoma albina (Sea snail) (Xenuroturris albina)
Neurotoxin Ion channel impairing toxin
Acts as a neurotoxin by inhibiting an ion channel (By similarity). May also act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature..
Turripeptide OL11-like
other
Conopeptide P-like superfamily
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Neurotoxin Protease inhibitor Secreted Serine protease inhibitor Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Disulfide bond Ion channel impairing toxin Neurotoxin Protease inhibitor Secreted Serine protease inhibitor Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Conopeptide P-like superfamily
Turripeptide OL11-like
TISSUE SPECIFICITY: Expressed by the venom duct.
other