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Peptide record

TPDB72512

Neurotoxin standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB72512
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 29-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
APALVVTATTNCCGYTGPACHPCLCTQTC
Physicochemical Analysis
C119H191N33O39S6
RDEIKMFSW
CT
2900.38
6.74
1
0
9
-0
0.13
0.583
60.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
64.30
15
Residue Composition
number
4
A
0
R
1
N
0
D
6
C
0
E
1
Q
2
G
1
H
0
I
2
L
0
K
0
M
0
F
3
P
0
S
6
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 6 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 2 K: 0 M: 0 F: 0 P: 3 S: 0 T: 6 W: 0 Y: 1 V: 2
Chemical Descriptors
29
C119H191N33O39S6
2900.38
6.74
-0
0.13
0.583
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with ion channel inhibitor activity. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus striatus (Striated cone)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with ion channel inhibitor activity..
Conotoxin SIVC (KappaA-conotoxin SIVC) (STR18)
cone snail
Conotoxin A superfamily
Evidence at protein level
Acetylation Amidation Direct protein sequencing Disulfide bond Glycoprotein Hydroxylation Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. Low expression in the distal venom duct sections. {ECO:0000269|PubMed:34168165}.
Additional Detail Fields 7 fields
Acetylation Amidation Direct protein sequencing Disulfide bond Glycoprotein Hydroxylation Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin A superfamily
Conotoxin SIVC (KappaA-conotoxin SIVC) (STR18)
TISSUE SPECIFICITY: Expressed by the venom duct. Low expression in the distal venom duct sections. {ECO:0000269|PubMed:34168165}.
cone snail