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Peptide record

TPDB72487

Neurotoxin standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB72487
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 63-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MECYKCGVSGCHLKITCSAEEKFCYKWRDKISNERWLGCAKTCTEENTWRVYNSCCTTNLCNP
Physicochemical Analysis
C311H480N88O96S11
Q
C
7340.42
7.72
10
7
17
+2
11.99
-0.584
43.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
21595
294.19
28
Residue Composition
number
2
A
3
R
5
N
1
D
10
C
6
E
0
Q
3
G
1
H
2
I
3
L
6
K
1
M
1
F
1
P
4
S
6
T
3
W
3
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 5 D: 1 C: 10 E: 6 Q: 0 G: 3 H: 1 I: 2 L: 3 K: 6 M: 1 F: 1 P: 1 S: 4 T: 6 W: 3 Y: 3 V: 2
Chemical Descriptors
63
C311H480N88O96S11
7340.42
7.72
+2
11.99
-0.584
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Unknown. In vitro, this toxin activates sperm motility when tested on OF1 male mice. {ECO:0000269|PubMed:29410678}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Walterinnesia aegyptia (Desert black snake)
Neurotoxin Presynaptic neurotoxin
Unknown. In vitro, this toxin activates sperm motility when tested on OF1 male mice..
Actiflagelin
snake
Three-finger toxin family, Ancestral subfamily, Orphan group XIX sub-subfamily
Evidence at protein level
Amidation Direct protein sequencing Disulfide bond Neurotoxin Presynaptic neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:29410678}.
Additional Detail Fields 7 fields
Amidation Direct protein sequencing Disulfide bond Neurotoxin Presynaptic neurotoxin Secreted Toxin
Neurotoxin Presynaptic neurotoxin
Evidence at protein level
Three-finger toxin family, Ancestral subfamily, Orphan group XIX sub-subfamily
Actiflagelin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:29410678}.
snake