Back to search

Peptide record

TPDB72486

Neurotoxin standard
104 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB72486
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 104-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
QACSETSDCLEGLECSGNQCLIPYDGDDSCVTGFDCVIGVGCVYDNGNPGRCIRDHRCKGDKKDICTNPATECDEDKVCGYKEGETCYGPCRKGLTCRNTRCQK
Physicochemical Analysis
C456H727N139O164S16
MW
C
11293.58
4.57
14
18
20
-6
35.49
-0.700
45.87
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6960
61.63
39
Residue Composition
number
2
A
6
R
5
N
11
D
16
C
7
E
3
Q
13
G
1
H
4
I
4
L
7
K
0
M
1
F
4
P
4
S
7
T
0
W
4
Y
5
V
Amino Acid Distribution
A: 2 R: 6 N: 5 D: 11 C: 16 E: 7 Q: 3 G: 13 H: 1 I: 4 L: 4 K: 7 M: 0 F: 1 P: 4 S: 4 T: 7 W: 0 Y: 4 V: 5
Chemical Descriptors
104
C456H727N139O164S16
11293.58
4.57
-6
35.49
-0.700
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Acts as a neurotoxin by inhibiting an ion channel. {ECO:0000250}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Iotyrris olangoensis (Sea snail) (Lophiotoma olangoensis)
Neurotoxin Ion channel impairing toxin
Acts as a neurotoxin by inhibiting an ion channel..
Turripeptide OL55
other
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 6 fields
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Turripeptide OL55
TISSUE SPECIFICITY: Expressed by the venom duct.
other