TPDB

3D PDB MODEL

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TPDB ID TPDB72475

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 183-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MLYKSSDRPAHKVSMLLLCHALAIAVVQIVIFSESWAFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQNTQYCLTVHHFTSHGRSTSITKKCASRSECHFVGCHHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSAPTLYLPVLAWVFVLPLL

FASTA

>TPDB72475|Neurotoxin|length=183
MLYKSSDRPAHKVSMLLLCHALAIAVVQIVIFSESWAFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQNTQYCLTVHHFTSHGRSTSITKKCASRSECHFVGCHHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSAPTLYLPVLAWVFVLPLL

Formula C913H1388N256O260S17

Absent Amino Acids

Common Amino Acids S

Mass 20655.64

PI 7.64

Basic Residues 26

Acidic Residues 13

Hydrophobic Residues 70

Net Charge +2

Boman Index 23.92

Hydrophobicity -0.129

Aliphatic Index 70.87

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 30200

Absorbance 280nm 146.21

Polar Residues 63

number

14

A

8

R

12

N

5

D

13

C

8

E

4

Q

5

G

11

H

6

I

14

L

7

K

4

M

10

F

11

P

17

S

12

T

4

W

5

Y

13

V

Amino Acid Distribution

A: 14 R: 8 N: 12 D: 5 C: 13 E: 8 Q: 4 G: 5 H: 11 I: 6 L: 14 K: 7 M: 4 F: 10 P: 11 S: 17 T: 12 W: 4 Y: 5 V: 13

Length

183

Formula

C913H1388N256O260S17

Mass

20655.64

PI

7.64

Net Charge

+2

Boman Index

23.92

Hydrophobicity

-0.129

Evidence 1 Activity

Source & Reference

Database Source NA