Back to search

Peptide record

TPDB72431

Neurotoxin standard
89 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB72431
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 89-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLTCVLIVAVLFLTACQLATAENSREEQGYSAVRSSDQIQDSDLKLTKSCTDDFEPCEAGFENCCSKSCFEFEDVYVCGVSIDYYDSR
Physicochemical Analysis
C426H660N108O147S9
HW
S
9935.10
3.94
7
16
33
-9
21.09
-0.106
73.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6460
65.02
33
Residue Composition
number
6
A
3
R
2
N
8
D
8
C
8
E
4
Q
3
G
0
H
3
I
7
L
4
K
1
M
5
F
1
P
10
S
5
T
0
W
4
Y
7
V
Amino Acid Distribution
A: 6 R: 3 N: 2 D: 8 C: 8 E: 8 Q: 4 G: 3 H: 0 I: 3 L: 7 K: 4 M: 1 F: 5 P: 1 S: 10 T: 5 W: 0 Y: 4 V: 7
Chemical Descriptors
89
C426H660N108O147S9
9935.10
3.94
-9
21.09
-0.106
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus bullatus (Bubble cone)
Neurotoxin Ion channel impairing toxin
Conotoxin Bu5
cone snail
Conotoxin O1 superfamily
Evidence at transcript level
Amidation Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Amidation Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Conotoxin O1 superfamily
Conotoxin Bu5
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail