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Peptide record

TPDB72426

Neurotoxin standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB72426
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 65-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MRCLSIFVLLVLLVSFAVAELDVEGEIVKQLLTRGTLKDADFWKRLEMQGCVCNANAKFCCGEGR
Physicochemical Analysis
C321H524N86O90S7
HPY
L
7252.63
6.34
8
8
31
-0
8.97
0.483
110.92
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5750
79.28
13
Residue Composition
number
5
A
4
R
2
N
3
D
5
C
5
E
2
Q
5
G
0
H
2
I
10
L
4
K
2
M
4
F
0
P
2
S
2
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 5 R: 4 N: 2 D: 3 C: 5 E: 5 Q: 2 G: 5 H: 0 I: 2 L: 10 K: 4 M: 2 F: 4 P: 0 S: 2 T: 2 W: 1 Y: 0 V: 7
Chemical Descriptors
65
C321H524N86O90S7
7252.63
6.34
-0
8.97
0.483
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target. Possibly targets ion channels. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Californiconus californicus (California cone) (Conus californicus)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target. Possibly targets ion channels..
Conotoxin Cal16.1 (Conotoxin Cal16a)
cone snail
Evidence at protein level
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
Additional Detail Fields 6 fields
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Pyrrolidone carboxylic acid Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin Cal16.1 (Conotoxin Cal16a)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
cone snail