TPDB

3D PDB MODEL

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TPDB ID TPDB72404

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 127-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MQGTWMVLLALILGTFGELAMALQCYTCANPVSASNCVTTTHCHINETMCKTTLYSLEIVFPFLGDSTVTKSCASKCEPSDVDGIGQTRPVSCCNSDLCNVDGAPSLGSPGGLLLALALFLLLGVLL

FASTA

>TPDB72404|Neurotoxin|length=127
MQGTWMVLLALILGTFGELAMALQCYTCANPVSASNCVTTTHCHINETMCKTTLYSLEIVFPFLGDSTVTKSCASKCEPSDVDGIGQTRPVSCCNSDLCNVDGAPSLGSPGGLLLALALFLLLGVLL

Formula C581H936N146O179S14

Absent Amino Acids

Common Amino Acids L

Mass 13279.53

PI 4.34

Basic Residues 6

Acidic Residues 9

Hydrophobic Residues 54

Net Charge -5

Boman Index 4.22

Hydrophobicity 0.620

Aliphatic Index 104.41

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 9105

Absorbance 280nm 68.56

Polar Residues 43

number

9

A

1

R

5

N

5

D

10

C

4

E

3

Q

11

G

2

H

4

I

21

L

3

K

4

M

4

F

6

P

11

S

12

T

1

W

2

Y

9

V

Amino Acid Distribution

A: 9 R: 1 N: 5 D: 5 C: 10 E: 4 Q: 3 G: 11 H: 2 I: 4 L: 21 K: 3 M: 4 F: 4 P: 6 S: 11 T: 12 W: 1 Y: 2 V: 9

Length

127

Formula

C581H936N146O179S14

Mass

13279.53

PI

4.34

Net Charge

-5

Boman Index

4.22

Hydrophobicity

0.620

Evidence 1 Activity

Source & Reference

Database Source NA