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Peptide record

TPDB72378

Neurotoxin standard
78 amino acids
Basic Information
3D PDB MODEL
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TPDB72378
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 78-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLTCVLIIAVLFLTAITADDSRDKQVYRAVGLIDKMRRIRASEGCRKKGDRCGTHLCCPGLRCGSGRAGGACRPPYN
Physicochemical Analysis
C359H609N117O102S9
W
R
8485.05
9.83
16
6
28
+9
14.04
-0.119
83.85
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
39.54
18
Residue Composition
number
7
A
10
R
1
N
5
D
7
C
1
E
1
Q
9
G
1
H
5
I
7
L
5
K
2
M
1
F
3
P
3
S
4
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 7 R: 10 N: 1 D: 5 C: 7 E: 1 Q: 1 G: 9 H: 1 I: 5 L: 7 K: 5 M: 2 F: 1 P: 3 S: 3 T: 4 W: 0 Y: 2 V: 4
Chemical Descriptors
78
C359H609N117O102S9
8485.05
9.83
+9
14.04
-0.119
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus bullatus (Bubble cone)
Neurotoxin Ion channel impairing toxin
Conotoxin Bu2
cone snail
Conotoxin O1 superfamily
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 7 fields
Disulfide bond Ion channel impairing toxin Knottin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Conotoxin O1 superfamily
Conotoxin Bu2
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail